Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.50 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.48 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833349 | 0.89 | SLC9A1 (0.50) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL7823576 | 0.89 | SLC9A1 (0.63) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL7823474 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7825457 | 0.88 | SLC9A1 (0.61) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8446576 | 0.87 | SLC9A1 (0.65) | SLC9A1SLC9A3SLC9A2 | |
| Hydrochloric Acid SCHEMBL7835986 | 0.87 | — | — | |
| SCHEMBL7838637 | 0.87 | SLC9A1 (0.51) | SLC9A1 | |
| SCHEMBL7835065 | 0.86 | SLC9A1 (0.48) | SLC9A1 | |
| SCHEMBL7835690 | 0.85 | SLC9A1 (0.47) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL7836974 | 0.85 | SLC9A1 (0.48) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667341-B1 | 4-Amino-1-piperidylbenzoylguanidines as Na+/H+ antiporter inhibitors | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | EP | disclosed |
| US-5461066-A | 4-amino-1-piperidylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-24 | — | — | US | disclosed |
| EP-0667341-A1 | 4-Amino-1-piperidylbenzoylguanidines as Na+/H+ antiporter inhibitors | MERCK PATENT GmbH (DE) | 1995-08-16 | — | — | EP | disclosed |