Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832589 | 0.89 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL11679397 | 0.84 | GRIN1 (0.44) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL11679389 | 0.84 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4CYP3A4HTR2A | |
| SCHEMBL11678040 | 0.84 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL29485914 | 0.83 | MEN1 (0.54) | SLC6A2SLC6A3SLC6A4MEN1TP53 | |
| SCHEMBL14707071 | 0.83 | MEN1 (0.54) | SLC6A2SLC6A3SLC6A4MEN1TP53 | |
| SCHEMBL11680046 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4HTR2AHTR2B | |
| SCHEMBL11678744 | 0.80 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4HTR2AHTR2B | |
| SCHEMBL11678606 | 0.79 | MEN1 (0.51) | SLC6A2SLC6A3SLC6A4MEN1TP53 | |
| SCHEMBL11680286 | 0.76 | DRD4 (0.54) | SLC6A2SLC6A3SLC6A4MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |