Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663231 | 0.80 | ALDH1A1 (0.44) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL2770405 | 0.78 | SLC6A2 (0.38) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL2770402 | 0.78 | SLC6A2 (0.38) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL7707686 | 0.78 | ABCB1 (0.35) | KMT2ASLC6A2SLC6A3TDP1ABCB1 | |
| SCHEMBL20444761 | 0.74 | ABCB1 (0.46) | KMT2AABCB1 | |
| SCHEMBL20960060 | 0.72 | ALDH1A1 (0.43) | KMT2ALMNAALDH1A1CYP2D6MAPK1 | |
| SCHEMBL1098278 | 0.72 | ALDH1A1 (0.42) | KMT2ALMNAABCB1ALDH1A1PRKCA | |
| SCHEMBL1098275 | 0.72 | ALDH1A1 (0.42) | KMT2ALMNAABCB1ALDH1A1PRKCA | |
| SCHEMBL4293682 | 0.71 | SLC6A2 (0.43) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL4293686 | 0.71 | SLC6A2 (0.43) | KMT2ASLC6A2SLC6A3TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161439-A1 | XYLO-LNA ANALOGUES | Exiqon A/S (DK) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000056748-A1 | XYLO-LNA ANALOGUES | EXIQON A/S (DK) | 2000-09-28 | — | — | WO | disclosed |