Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945644 | 0.88 | PTPN1 (0.67) | PTPN1PTPN2PTPRC | |
| SCHEMBL6945668 | 0.84 | PTPN1 (0.58) | PTPN1PTPN2PTPRC | |
| SCHEMBL7832767 | 0.82 | PTPN1 (0.70) | PTPN1PTPN2PTPRC | |
| SCHEMBL7832783 | 0.78 | PTPN1 (0.60) | PTPN1PTPN2PTPRC | |
| SCHEMBL7166517 | 0.78 | PTPN1 (1.00) | PTPN1PTPN2 | |
| SCHEMBL7622074 | 0.74 | PTPN1 (0.71) | PTPN1PTPN2 | |
| SCHEMBL6950197 | 0.73 | PTPN1 (0.66) | PTPN1PTPN2PTPRC | |
| SCHEMBL7161699 | 0.63 | PTPN1 (1.00) | PTPN1PTPN2PTPRC | |
| SCHEMBL29240033 | 0.63 | PTPN1 (0.67) | PTPN1PTPN2 | |
| SCHEMBL6203944 | 0.62 | EPHX1 (0.65) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115729-A1 | PHOSPHONIC ACID DERIVATIVES AS INHIBITORS OF PTP-1B | Merck Frosst Canada & Co. (CA) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017211-A1 | PHOSPHONIC ACIDS DERIVATIVES AS INHIBITORS OF PTP-1B | MERCK FROSST CANADA & CO. (CA) | 2000-03-30 | — | — | WO | disclosed |