SCHEMBL783313

SCHEMBL783313

[O-][n+]1c(Br)cccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL943724 0.81
SCHEMBL5865099 0.75 GABRA1 (0.38)
SCHEMBL29962993 0.72 HDAC8 (0.30)
SCHEMBL11865337 0.71 TDP1 (0.34)
SCHEMBL11865588 0.70 HPGD (0.33)
Hydrochloric Acid SCHEMBL29653351 0.67
SCHEMBL2089464 0.67 CYP3A4 (0.32)
SCHEMBL15452637 0.67
Perchlorate SCHEMBL11802598 0.65 HDAC8 (0.42)
Bromide SCHEMBL29281367 0.65 CYP3A4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724805-B Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-11-01 CN claimed
CN-118724805-A Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-10-01 CN claimed
CN-111072559-B Construction and application of 2, 6-dibromopyridine oxidation system 浙江工商大学 2021-06-18 CN claimed
CN-111072559-A Construction and application of 2, 6-dibromopyridine oxidation system 浙江工商大学 2020-04-28 CN claimed
CN-118724805-B Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-11-01 CN disclosed
CN-118724805-A Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-10-01 CN disclosed
CN-117903048-A Synthesis method of 4-bromo-2, 6-diaminopyridine 苏州艾缇克药物化学有限公司 2024-04-19 CN disclosed
CN-111072559-B Construction and application of 2, 6-dibromopyridine oxidation system 浙江工商大学 2021-06-18 CN disclosed
CN-112745261-A Electron transport material, method for producing the same, electronic device, and display device 广东聚华印刷显示技术有限公司 2021-05-04 CN disclosed
CN-111072559-A Construction and application of 2, 6-dibromopyridine oxidation system 浙江工商大学 2020-04-28 CN disclosed
EP-3613730-A1 METHOD FOR PRODUCING PYRIDINE COMPOUND Sumitomo Chemical Company, Limited (JP) 2020-02-26 EP disclosed
CN-110520411-A The manufacturing method of pyridine compounds SUMITOMO CHEMICAL CO 2019-11-29 CN disclosed
WO-2005026164-A1 PHARMACOLOGICALLY ACTIVE IMIDAZO[4,5-C]PYRIDINES ALTANA PHARMA AG (DE) 2005-03-24 WO disclosed
EP-0763033-B1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RES INST CHEM TECH (KR) 2002-10-16 EP disclosed
EP-0819118-B1 POTASSIUM ION CHANNEL BLOCKERS POLYCHIP PHARMACEUTICALS PTY (AU) 2002-09-18 EP disclosed
US-5929082-A SULFONYL(THIO)UREA AND SULFONYLGUANIDINE COMPOUNDS; TREATMENT OF DIABETES, CARDIAC ARRHYTHMIAS, ISCHEMIA, HYPOXIC CARDIOVASCUALR DISORDERS AND CANCER POLYCHIP PHARMACEUTICALS PTY LTD (AU) 1999-07-27 US disclosed
EP-0819118-A4 POTASSIUM ION CHANNEL BLOCKERS POLYCHIP PHARMACEUTICALS PTY (AU) 1998-04-29 EP disclosed
EP-0819118-A1 POTASSIUM ION CHANNEL BLOCKERS Polychip Pharmaceuticals Pty. Ltd. (AU) 1998-01-21 EP disclosed
US-5665738-A HYPOTENSIVE AGENTS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-09-09 US disclosed
WO-1996030341-A1 POTASSIUM ION CHANNEL BLOCKERS POLYCHIP PHARMACEUTICALS PTY. LTD. (AU) 1996-10-03 WO disclosed