SCHEMBL7833233

SCHEMBL7833233

CC(C(=O)N1CCC(CC(=O)O)CC1)C(C)(C)NC(=O)c1ccc(C(=N)N)cc1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.70
ITGA2B P08514 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7826348 0.90 ITGB3 (0.68) ITGB3ITGA2B
SCHEMBL7837531 0.89 ITGB3 (0.67) ITGB3ITGA2B
SCHEMBL7825957 0.88 ITGB3 (0.68) ITGB3ITGA2B
SCHEMBL7362817 0.88 ITGB3 (0.70) ITGB3ITGA2B
SCHEMBL7833511 0.88 ITGB3 (0.65) ITGB3ITGA2B
SCHEMBL7835723 0.87 ITGB3 (0.68) ITGB3ITGA2B
SCHEMBL7360590 0.86 ITGB3 (0.63) ITGB3ITGA2B
SCHEMBL7836547 0.86 ITGB3 (0.67) ITGB3ITGA2B
SCHEMBL8789526 0.85 ITGB3 (0.70) ITGB3ITGA2B
SCHEMBL7358390 0.85 ITGB3 (0.67) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0800516-B1 FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME NIPPON STEEL CORP (JP) 2001-09-19 EP disclosed
US-5866592-A Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same NIPPON STEEL CORPORATION (JP) 1999-02-02 US disclosed