Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.31 |
| ▸ | CDC25B | P30305 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832335 | 0.78 | HSD17B10 (0.44) | LMNAHSD17B10ALOX15 | |
| SCHEMBL12588552 | 0.72 | LMNA (0.43) | LMNABLMFNTAPGGT1BMMP9 | |
| SCHEMBL11795028 | 0.69 | HSD17B10 (0.73) | LMNAHSD17B10 | |
| SCHEMBL6271680 | 0.67 | BLM (0.56) | LMNABLMPTPN1PTPN2CDC25B | |
| SCHEMBL1786816 | 0.66 | BLM (0.54) | LMNABLMPTPN1PTPN2CDC25B | |
| SCHEMBL1683970 | 0.66 | BLM (0.59) | LMNABLMPTPN1ALOX15 | |
| SCHEMBL8626585 | 0.66 | BLM (0.59) | LMNABLMPTPN1ALOX15 | |
| SCHEMBL9858195 | 0.66 | BLM (0.59) | LMNABLMPTPN1ALOX15 | |
| Phytanic Acid SCHEMBL3819827 | 0.64 | BLM (0.63) | LMNABLMPTPN1ALOX15 | |
| SCHEMBL12713322 | 0.64 | BLM (0.57) | LMNABLMPTPN1PTPN2CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064269-A1 | BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME | Hoechst Marion Roussel (FR) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999050252-A2 | BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME | HOECHST MARION ROUSSEL (FR) | 1999-10-07 | — | — | WO | disclosed |