Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 8/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470390 | 0.89 | CALML3 (0.48) | CALML3MAOAMAOBGRM2CYP2C19 | |
| SCHEMBL7000748 | 0.86 | CALML3 (0.42) | CALML3MAOAMAOBGRM2 | |
| SCHEMBL7845157 | 0.77 | GRM2 (0.41) | CALML3MAOAGRM2 | |
| SCHEMBL3323276 | 0.77 | CALML3 (0.80) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL3323285 | 0.77 | CALML3 (0.80) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL3323279 | 0.77 | CALML3 (0.80) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL5625330 | 0.76 | CALML3 (0.58) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL5236580 | 0.76 | CALML3 (0.58) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL6925097 | 0.76 | CALML3 (0.58) | CALML3MAOAMAOBCYP2C19CYP2C9 | |
| SCHEMBL7140238 | 0.76 | GRM2 (0.41) | CALML3MAOBGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |