Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.68 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CALML3 | P27482 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323189 | 0.89 | MAOA (0.79) | MAOACYP2E1CALML3CYP3A4CYP2D6 | |
| SCHEMBL3323187 | 0.89 | MAOA (0.79) | MAOACYP2E1CALML3CYP3A4CYP2D6 | |
| SCHEMBL3323196 | 0.89 | MAOA (0.79) | MAOACYP2E1CALML3CYP3A4CYP2D6 | |
| SCHEMBL7845433 | 0.85 | MAOA (0.72) | MAOACYP2E1CALML3CYP3A4CYP2C19 | |
| SCHEMBL15830253 | 0.81 | MAOA (0.68) | MAOACYP2E1CALML3MAOB | |
| SCHEMBL7840408 | 0.81 | CALML3 (0.70) | MAOACALML3CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8822103 | 0.81 | MAOA (0.66) | MAOACALML3MAOB | |
| SCHEMBL463398 | 0.81 | MAOA (0.60) | MAOACYP2E1CALML3CYP3A4CYP2C19 | |
| SCHEMBL6639743 | 0.80 | MAOA (0.67) | MAOACYP2E1CALML3MAOB | |
| SCHEMBL5832800 | 0.79 | MAOA (0.66) | MAOACYP2E1CALML3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |