Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842187 | 0.94 | CFTR (0.42) | KMT2AHSD17B10GABRA1GABRB1GABRA3 | |
| SCHEMBL7845627 | 0.84 | KDM4E (0.44) | KMT2AHSD17B10GABRA1GABRB2CFTR | |
| SCHEMBL7858072 | 0.83 | HSD17B10 (0.46) | KMT2AHSD17B10GABRA1GABRB1GABRA3 | |
| SCHEMBL7834426 | 0.83 | HSD17B10 (0.46) | KMT2AHSD17B10GABRA1GABRB1GABRA3 | |
| SCHEMBL7845731 | 0.81 | HSD17B10 (0.44) | KMT2AHSD17B10GABRA1GABRB1GABRA3 | |
| SCHEMBL7845316 | 0.81 | HSD17B10 (0.44) | KMT2AHSD17B10GABRA1GABRB2CFTR | |
| SCHEMBL7846612 | 0.79 | HSD17B10 (0.41) | KMT2AHSD17B10GABRA1GABRB2CFTR | |
| SCHEMBL7846115 | 0.78 | HSD17B10 (0.42) | KMT2AHSD17B10GABRA1GABRB1GABRA3 | |
| SCHEMBL7834337 | 0.78 | KDM4E (0.49) | KMT2AHSD17B10GABRA1GABRB1GABRA3 | |
| SCHEMBL7847448 | 0.77 | GABRA1 (0.44) | GABRA1GABRB1GABRA3GABRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |