Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834802 | 1.00 | HRH3 (0.35) | HRH3PTPRCEPHX2MAPTL3MBTL1 | |
| SCHEMBL7834806 | 1.00 | HRH3 (0.35) | HRH3PTPRCEPHX2MAPTL3MBTL1 | |
| SCHEMBL785469 | 0.85 | L3MBTL1 (0.36) | HRH3PTPRCEPHX2L3MBTL1ABCB1 | |
| SCHEMBL7834319 | 0.83 | MAPT (0.33) | HRH3PTPRCEPHX2MAPTL3MBTL1 | |
| SCHEMBL7834326 | 0.83 | MAPT (0.33) | HRH3PTPRCEPHX2MAPTL3MBTL1 | |
| SCHEMBL7834322 | 0.83 | MAPT (0.33) | HRH3PTPRCEPHX2MAPTL3MBTL1 | |
| SCHEMBL3198780 | 0.75 | GAA (0.43) | EPHX2 | |
| SCHEMBL4527860 | 0.75 | GAA (0.43) | EPHX2 | |
| SCHEMBL3198789 | 0.75 | GAA (0.43) | EPHX2 | |
| SCHEMBL3564060 | 0.75 | GAA (0.43) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787726-B1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5817669-A | A COMPOUND CONTAINING 1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0787726-A1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |