Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890450 | 0.85 | TTR (0.43) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL28490896 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1POLBTDP1HPGD | |
| SCHEMBL28497189 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1POLBTDP1HPGD | |
| SCHEMBL4871137 | 0.74 | IP6K1 (0.41) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL4871141 | 0.74 | IP6K1 (0.41) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL24621918 | 0.74 | CNR1 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL4865191 | 0.73 | IP6K1 (0.43) | KDM4EPOLBTDP1HPGDSMN1; SMN2 | |
| SCHEMBL4865182 | 0.73 | IP6K1 (0.43) | KDM4EPOLBTDP1HPGDSMN1; SMN2 | |
| SCHEMBL7309566 | 0.73 | KDM4E (0.80) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL21002107 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |