Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309562 | 1.00 | KDM4E (0.80) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| Pyrrolidine SCHEMBL22397855 | 0.93 | KDM4E (0.70) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL15681760 | 0.91 | ALDH1A1 (0.67) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL21002107 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL23728133 | 0.82 | KDM4E (0.65) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL23728132 | 0.82 | KDM4E (0.65) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| Isomyristicin SCHEMBL30678763 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL31493163 | 0.81 | ALDH1A1 (0.53) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL7199637 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL30365889 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-0628311-B1 | Xanthine-Derivatives as Antidepressants | KYOWA HAKKO KOGYO KK (JP) | 2002-04-24 | — | — | EP | disclosed |
| US-5587378-A | ADMINISTERING A SUBSTITUTED XANTHINE COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5543415-A | ADMINISTERING A XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| US-5484920-A | XANTHINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0628311-A1 | ANTIDEPRESSANT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0590919-A1 | Therapeutic agents for parkinson's disease | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |