Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.89 |
| ▸ | HTT | P42858 | 2/20 | 0.89 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.89 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835431 | 1.00 | SMN1; SMN2 (0.89) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| Methane SCHEMBL7997331 | 0.99 | SMN1; SMN2 (0.86) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL6645560 | 0.98 | SMN1; SMN2 (0.91) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL243430 | 0.94 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL4700801 | 0.88 | HTT (0.69) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL1269672 | 0.88 | SMN1; SMN2 (0.82) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL4703104 | 0.87 | HTT (0.71) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL27509034 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL8593944 | 0.85 | HTT (0.65) | SMN1; SMN2HTTALOX15LMNAHPGD | |
| SCHEMBL7829459 | 0.85 | LMNA (0.67) | SMN1; SMN2HTTALOX15LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |