Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837039 | 0.94 | CCR5 (0.79) | CCR5 | |
| SCHEMBL8082673 | 0.91 | CCR5 (0.69) | CCR5 | |
| SCHEMBL7829490 | 0.90 | CCR5 (0.85) | CCR5 | |
| SCHEMBL7863124 | 0.88 | CCR5 (0.60) | CCR5 | |
| SCHEMBL7871240 | 0.88 | CCR5 (0.54) | CCR5 | |
| SCHEMBL7871243 | 0.88 | CCR5 (0.54) | CCR5 | |
| SCHEMBL7826310 | 0.88 | CCR5 (0.78) | CCR5 | |
| SCHEMBL7863129 | 0.86 | CCR5 (0.66) | CCR5 | |
| SCHEMBL7870867 | 0.86 | CCR5 (0.72) | CCR5 | |
| SCHEMBL7687718 | 0.85 | CCR5 (0.50) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009405-A4 | PYRROLIDINE AND PIPERIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO INC (US) | 2001-05-09 | — | — | EP | disclosed |
| US-6166037-A | Pyrrolidine and piperidine modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-1009405-A1 | PYRROLIDINE AND PIPERIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999009984-A1 | PYRROLIDINE AND PIPERIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |