Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655083 | 0.88 | F2 (0.42) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10652362 | 0.84 | F2 (0.56) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL6677573 | 0.82 | GAA (0.36) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL6580084 | 0.80 | F2 (0.65) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL9840763 | 0.79 | F2 (0.68) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5654332 | 0.77 | CYP3A4 (0.43) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL11870981 | 0.77 | PRSS1 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5610254 | 0.77 | F2 (0.61) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10883679 | 0.76 | CA1 (0.61) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL11042682 | 0.75 | MAPT (0.51) | F2PRSS1PRSS2PRSS3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10287801-A | — | — | None | — | — | JP | disclosed |
| US-9855230-B2 | Inhibitors of human immunodeficiency virus replication | VIIV Healthcare UK (No.5) Limited (GB) | 2018-01-02 | — | — | US | disclosed |
| US-20170304239-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2017-10-26 | — | — | US | disclosed |
| WO-2016040084-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-03-17 | — | — | WO | disclosed |
| US-9133363-B2 | Stabilized urethane based surface coating | BLUM HOLGER (CH) | 2015-09-15 | — | — | US | disclosed |
| US-20150011690-A1 | STABILIZED URETHANE BASED SURFACE COATING | BLUM HOLGER (CH) | 2015-01-08 | — | — | US | disclosed |
| EP-2686358-B1 | STABILIZED URETHANE BASED SURFACE COATING | BLUM HOLGER (CH) | 2014-11-19 | — | — | EP | disclosed |
| EP-2686358-A1 | STABILIZED URETHANE BASED SURFACE COATING | Blum, Holger (CH) | 2014-01-22 | — | — | EP | disclosed |
| WO-2013139388-A1 | STABILIZED URETHANE BASED SURFACE COATING | BLUM HOLGER (CH) | 2013-09-26 | — | — | WO | disclosed |
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| EP-0030141-B1 | HERBICIDAL UREAS AND ISOUREAS, PREPARATION, COMPOSITIONS AND USE THEREOF, INTERMEDIATES THEREFOR AND PREPARATION OF SAID INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4452627-A | HERBICIDE, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4425155-A | 1,2,4-TRIAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-10 | — | — | US | disclosed |
| US-4421550-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0073562-A2 | Herbicidal triazole ureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-03-09 | — | — | EP | disclosed |
| US-4370479-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| EP-0057546-A2 | Sulfonylurea N-oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |
| US-4169719-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND CO. (US) | 1979-10-02 | — | — | US | disclosed |
| US-4127405-A | TRIAZINYL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304239-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2E, POLR2H | F2 3861/4885PRSS1 868/4885PRSS2 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.