Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6160447 | 0.99 | POLB (0.37) | POLBAPPP2RX7GAAL3MBTL1 | |
| SCHEMBL7837719 | 0.92 | MAP4K1 (0.37) | POLBAPPALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6159322 | 0.91 | MAP4K1 (0.37) | POLBAPPALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7159588 | 0.91 | POLB (0.36) | POLBAPPP2RX7GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6158437 | 0.91 | GALR2 (0.34) | P2RX7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6158464 | 0.91 | POLB (0.37) | POLBAPPP2RX7GAAL3MBTL1 | |
| SCHEMBL7831079 | 0.88 | MAP4K1 (0.36) | NPC1RAB9AKMT2A | |
| SCHEMBL6158156 | 0.88 | KMT2A (0.40) | APPGAAL3MBTL1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL6160999 | 0.87 | MAP4K1 (0.35) | NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL6157511 | 0.87 | KMT2A (0.39) | APPGAAL3MBTL1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |