Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6159322 | 0.99 | MAP4K1 (0.37) | MAP4K1POLBRAB9AAPPKDM4E | |
| SCHEMBL7831079 | 0.92 | MAP4K1 (0.36) | MAP4K1RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL7835366 | 0.92 | POLB (0.38) | POLBRAB9AAPPNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6158963 | 0.91 | MAP4K1 (0.37) | MAP4K1POLBRAB9AAPPKDM4E | |
| Hydrochloric Acid SCHEMBL6160999 | 0.91 | MAP4K1 (0.35) | MAP4K1RAB9ANPC1NFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL6160447 | 0.91 | POLB (0.37) | POLBRAB9AAPPNPC1ALDH1A1 | |
| SCHEMBL6158484 | 0.88 | KDM4E (0.35) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7159588 | 0.88 | POLB (0.36) | MAP4K1POLBRAB9AAPPKDM4E | |
| Hydrochloric Acid SCHEMBL27566512 | 0.87 | KDM4E (0.31) | KDM4ENPSR1MTNR1B | |
| Hydrochloric Acid SCHEMBL6158437 | 0.87 | GALR2 (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |