Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.69 |
| ▸ | PPARA | Q07869 | 6/20 | 0.69 |
| ▸ | PPARG | P37231 | 9/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823056 | 0.91 | FFAR1 (0.72) | FFAR1PPARAPPARG | |
| SCHEMBL7836370 | 0.88 | FFAR1 (0.65) | FFAR1PPARAPPARGTP53MAPT | |
| SCHEMBL6903005 | 0.84 | PPARG (0.73) | FFAR1PPARAPPARGESRRA | |
| SCHEMBL7837758 | 0.82 | PPARG (0.65) | FFAR1PPARAPPARGESRRA | |
| SCHEMBL7831811 | 0.78 | PPARG (0.61) | FFAR1PPARAPPARGESRRA | |
| SCHEMBL5844579 | 0.78 | PPARG (0.80) | FFAR1PPARAPPARGESRRA | |
| SCHEMBL7835362 | 0.78 | PPARG (0.61) | FFAR1PPARAPPARGESRRA | |
| SCHEMBL11066932 | 0.77 | FFAR1 (0.77) | FFAR1PPARAPPARGTP53MAPT | |
| SCHEMBL6900101 | 0.76 | PPARG (0.68) | FFAR1PPARAPPARGTP53MAPT | |
| SCHEMBL7243295 | 0.76 | PPARG (0.81) | FFAR1PPARAPPARGESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676398-B1 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6117893-A | Heterocyclic compounds having anti-diabetic activity and their use | SANKYO COMPANY, LIMITED (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-1022274-A1 | Oxazolidinedione and Thiazolidinedione derivatves, their preparation and their use | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5977365-A | HYPOGLYCEMIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5962470-A | Heterocyclic compounds having anti-diabetic activity and their use | SANKYO COMPANY, LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5834501-A | TREATING DIABETES OR HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |