Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.67 |
| ▸ | GABRP | O00591 | 1/20 | 0.56 |
| ▸ | GABRD | O14764 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.56 |
| ▸ | GABRE | P78334 | 1/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17796014 | 0.89 | GAA (0.62) | GAANR4A2GABRPGABRDGABRA1 | |
| SCHEMBL27626028 | 0.89 | NR4A2 (0.65) | GAANR4A2GABRPGABRDGABRA1 | |
| SCHEMBL18932679 | 0.87 | NR4A2 (0.67) | GAANR4A2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL2005093 | 0.86 | GAA (1.00) | GAAALOX5HSD17B10ALDH1A1KDM4E | |
| SCHEMBL31286098 | 0.86 | GAA (1.00) | GAAALOX5HSD17B10ALDH1A1KDM4E | |
| SCHEMBL11790716 | 0.85 | GAA (0.68) | GAANR4A2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL7815779 | 0.85 | GAA (0.68) | GAANR4A2GABRPGABRDGABRA1 | |
| SCHEMBL7831236 | 0.85 | GAA (0.67) | GAANR4A2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL18919114 | 0.84 | ALDH1A1 (0.65) | GAANR4A2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL5236009 | 0.84 | NR4A2 (0.63) | GAANR4A2ALOX5HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1344270-A | Functionalized heterocycles as chemokine receptor modulators | THOUSAND YEARS MEDICAMENTS INC (US) | 2002-04-10 | — | — | CN | disclosed |
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |