Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.43 |
| ▸ | PPARG | P37231 | 16/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834133 | 0.96 | PPARA (0.44) | PPARAPPARGL3MBTL1 | |
| SCHEMBL7837126 | 0.82 | PPARA (0.52) | PPARAPPARGGAAMAPTL3MBTL1 | |
| SCHEMBL7837124 | 0.82 | PPARA (0.52) | PPARAPPARGGAAMAPTL3MBTL1 | |
| SCHEMBL7834782 | 0.81 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL7834780 | 0.81 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL6160170 | 0.81 | TBXAS1 (0.48) | PPARAPPARG | |
| SCHEMBL6160162 | 0.81 | TBXAS1 (0.48) | PPARAPPARG | |
| SCHEMBL6160171 | 0.81 | TBXAS1 (0.48) | PPARAPPARG | |
| SCHEMBL6158748 | 0.80 | TBXAS1 (0.49) | PPARAPPARG | |
| SCHEMBL6158746 | 0.80 | TBXAS1 (0.49) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077957-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058510-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-18 | — | — | WO | disclosed |