Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836666 | 1.00 | MEN1 (0.47) | MEN1KMT2AEHMT2CYP3A4TSHR | |
| SCHEMBL4606172 | 0.82 | MEN1 (0.53) | MEN1KMT2AEHMT2CYP3A4TSHR | |
| SCHEMBL7536658 | 0.82 | MEN1 (0.53) | MEN1KMT2AEHMT2CYP3A4TSHR | |
| SCHEMBL7847727 | 0.79 | MEN1 (0.50) | MEN1KMT2AEHMT2CYP3A4TSHR | |
| SCHEMBL7847725 | 0.79 | MEN1 (0.50) | MEN1KMT2AEHMT2CYP3A4TSHR | |
| SCHEMBL19387511 | 0.77 | MEN1 (0.58) | MEN1KMT2AEHMT2CYP3A4TSHR | |
| SCHEMBL17961690 | 0.72 | EHMT2 (0.45) | MEN1KMT2AEHMT2ELANEGSK3A | |
| SCHEMBL7849017 | 0.70 | THRB (0.38) | MEN1KMT2AEHMT2ELANECES2 | |
| SCHEMBL28273174 | 0.70 | TSHR (0.48) | MEN1KMT2AEHMT2CYP3A4TSHR | |
| SCHEMBL21066468 | 0.69 | BCHE (0.43) | MEN1KMT2AEHMT2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911336-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-6017911-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0911336-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-04-28 | — | — | EP | disclosed |