Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824400 | 0.88 | PTGS1 (0.49) | TTPATHRBCA1CA2MMP1 | |
| SCHEMBL7835467 | 0.87 | TTPA (0.52) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL7824921 | 0.84 | TTPA (0.49) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8419339 | 0.84 | TTPA (0.54) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL7825046 | 0.82 | TTPA (0.56) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL7836851 | 0.81 | TTPA (0.51) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL7836663 | 0.80 | TTPA (0.53) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL7835312 | 0.80 | TTPA (0.55) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL7825923 | 0.80 | TTPA (0.55) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL7836231 | 0.80 | TTPA (0.55) | TTPAALOX5MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844245-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0844245-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-27 | — | — | EP | disclosed |