SCHEMBL7836993

SCHEMBL7836993

Clc1ccc(-c2ccc(-c3ccc(Oc4ccccc4)cc3)c3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.53
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
GAA P10253 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CYP1A2 P05177 2/20 0.46
LTA4H P09960 5/20 0.46
TSHR P16473 2/20 0.46
MAOA P21397 2/20 0.45
MAOB P27338 1/20 0.45
PGR P06401 2/20 0.45
PTGS2 P35354 1/20 0.44
MAPK13 O15264 1/20 0.43
GCGR P47871 1/20 0.43
MAPK12 P53778 1/20 0.43
MAPK11 Q15759 1/20 0.43
MAPK14 Q16539 1/20 0.43
DHODH Q02127 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21214803 0.83 CYP1A2 (0.67) MEN1GAAKMT2ASMN1; SMN2CYP1A2
SCHEMBL30363359 0.83 CYP1A2 (0.67) MEN1GAAKMT2ASMN1; SMN2CYP1A2
SCHEMBL12295925 0.83 CYP1A2 (0.57) GAAKMT2ACYP1A2TSHRPTGS2
SCHEMBL196125 0.83 LTA4H (0.67) MEN1NPC1GAARAB9AKMT2A
SCHEMBL28298032 0.82 GSTP1 (0.51) GSTP1MEN1NPC1GAARAB9A
SCHEMBL24476798 0.81 CYP1A2 (0.71) GSTP1MEN1NPC1GAARAB9A
1,2-Dichlorobenzene SCHEMBL3984116 0.77 LTA4H (0.57) MEN1NPC1GAARAB9AKMT2A
SCHEMBL21205975 0.77 CYP1A2 (0.64) MEN1GAAKMT2ASMN1; SMN2CYP1A2
SCHEMBL27018972 0.77 CYP1A2 (0.58) GSTP1MEN1NPC1GAARAB9A
Diphenylether SCHEMBL1118926 0.76 LTA4H (0.71) MEN1NPC1GAARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752451-B1 The use of 4,5-dihydro-1H-1,2,3-triazolium cationic compounds as dyestuffs BAYER AG (DE) 2001-10-17 EP disclosed