Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.51 |
| ▸ | TUBB | P07437 | 4/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837150 | 1.00 | MEN1 (0.56) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7836500 | 0.91 | ABCG2 (0.53) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7836507 | 0.91 | ABCG2 (0.53) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7835579 | 0.88 | ALDH1A1 (0.73) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7833189 | 0.88 | MEN1 (0.57) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7833184 | 0.88 | MEN1 (0.57) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7835590 | 0.88 | ALDH1A1 (0.73) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7836422 | 0.87 | TUBB1 (0.57) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7836420 | 0.87 | TUBB1 (0.57) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7838733 | 0.87 | TNFRSF1A (0.67) | MEN1NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680950-B1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5952355-A | 1-ETHER-SUBSTITUTED PHENYL-3-INDOL-3-YL-2-PROPEN-1-ONE DERIVATIVES; ANTITUMOR AND -CARCINOGENIC AGENTS; IMMUNOSUPPRESSANTS; AUTOIMMUNE DISEASES; SIDE EFFECT REDUCTION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0680950-A1 | PROPENONE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-11-08 | — | — | EP | disclosed |