Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838728 | 0.86 | MCHR1 (0.75) | MCHR1HRH3ACHEMAOABCHE | |
| SCHEMBL7850512 | 0.84 | MCHR1 (0.57) | MCHR1HRH3ACHEMAOABCHE | |
| Hydrochloric Acid SCHEMBL7852567 | 0.84 | MCHR1 (0.57) | MCHR1HRH3ACHEMAOABCHE | |
| Hydrochloric Acid SCHEMBL7846320 | 0.84 | HRH3 (0.57) | MCHR1HRH3ACHEMAOABCHE | |
| Hydrochloric Acid SCHEMBL7848570 | 0.83 | HRH3 (0.49) | HRH3ACHEMAOABCHEMAOB | |
| SCHEMBL7850491 | 0.83 | HRH3 (0.47) | MCHR1HRH3ACHEMAOABCHE | |
| SCHEMBL7838199 | 0.81 | MCHR1 (0.63) | MCHR1HRH3ACHEMAOAMAOB | |
| SCHEMBL7847045 | 0.80 | HRH3 (0.49) | HRH3ACHEMOGAT2F10 | |
| SCHEMBL7846418 | 0.80 | MCHR1 (0.64) | MCHR1HRH3ACHEMAOABCHE | |
| Hydrochloric Acid SCHEMBL7847359 | 0.79 | F10 (0.49) | HRH3ACHEMAOABCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | claimed |
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |