Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850512 | 0.93 | MCHR1 (0.57) | MCHR1HRH3ACHEACACBBCHE | |
| Hydrochloric Acid SCHEMBL7852567 | 0.92 | MCHR1 (0.57) | MCHR1HRH3ACHEACACBBCHE | |
| SCHEMBL7838728 | 0.92 | MCHR1 (0.75) | MCHR1HRH3ACHEACACBBCHE | |
| SCHEMBL7848716 | 0.88 | MCHR1 (0.52) | MCHR1HRH3ACHEACACBBCHE | |
| Hydrochloric Acid SCHEMBL7850453 | 0.86 | HRH3 (0.47) | MCHR1HRH3ACHEACACBBCHE | |
| SCHEMBL7850551 | 0.86 | HRH3 (0.47) | MCHR1HRH3ACHEACACBBCHE | |
| Hydrochloric Acid SCHEMBL7847077 | 0.84 | ACHE (0.47) | MCHR1HRH3ACHEACACBBCHE | |
| Hydrochloric Acid SCHEMBL7854120 | 0.84 | HRH3 (0.46) | MCHR1HRH3ACHEACACBBCHE | |
| SCHEMBL7838199 | 0.84 | MCHR1 (0.63) | MCHR1HRH3ACHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL7847596 | 0.84 | MAOA (0.44) | MCHR1HRH3ACHEACACBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | claimed |
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |