Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273378 | 0.88 | TLR7 (0.62) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL29508382 | 0.81 | TLR7 (1.00) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL189202 | 0.81 | TLR7 (1.00) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL7834768 | 0.76 | TLR7 (0.71) | TLR7NUDT1TLR8 | |
| SCHEMBL8522286 | 0.75 | TLR7 (0.87) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL1486435 | 0.73 | TLR7 (0.70) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL27661125 | 0.71 | TLR7 (0.63) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL4531160 | 0.70 | TLR7 (0.71) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL6710596 | 0.70 | TLR7 (0.79) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL27661087 | 0.70 | TLR7 (0.65) | TLR7ADORA2ANUDT1PDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | disclosed |