Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.87 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508382 | 0.93 | TLR7 (1.00) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL189202 | 0.93 | TLR7 (1.00) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL6710596 | 0.82 | TLR7 (0.79) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL5617088 | 0.80 | TLR7 (0.74) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL1895460 | 0.79 | TLR7 (0.73) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL4144585 | 0.78 | TLR7 (0.71) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL4531160 | 0.77 | TLR7 (0.71) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL4531190 | 0.77 | TLR7 (0.71) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL1486435 | 0.77 | TLR7 (0.70) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL5617005 | 0.77 | TLR7 (0.70) | TLR7NUDT1LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912565-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997048704-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |