Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 13/20 | 0.84 |
| ▸ | PRKCA | P17252 | 12/20 | 0.84 |
| ▸ | PRKCE | Q02156 | 9/20 | 0.83 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | JAK1 | P23458 | 1/20 | 0.60 |
| ▸ | TYK2 | P29597 | 1/20 | 0.60 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | PRKACA | P17612 | 2/20 | 0.51 |
| ▸ | PRKACG | P22612 | 2/20 | 0.51 |
| ▸ | PRKACB | P22694 | 2/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840532 | 0.99 | PRKCB (0.84) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7839539 | 0.92 | PRKCB (1.00) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7843569 | 0.91 | PRKCB (1.00) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7832843 | 0.91 | PRKCB (1.00) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7839507 | 0.89 | PRKCB (0.81) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7841458 | 0.88 | PRKCB (0.78) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7841228 | 0.87 | PRKCB (0.77) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7845246 | 0.87 | PRKCB (0.77) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7831894 | 0.86 | PRKCB (0.76) | PRKCBPRKCAPRKCEJAK2JAK1 | |
| SCHEMBL7831659 | 0.86 | PRKCB (1.00) | PRKCBPRKCAPRKCEJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | claimed |
| WO-2013029043-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2013-02-28 | — | — | WO | disclosed |
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |