Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487273 | 0.86 | NPSR1 (0.49) | KDM4EMAPK1LMNAPOLBALDH1A1 | |
| SCHEMBL2734988 | 0.83 | KDM4E (0.47) | KDM4EMAPK1LMNAPOLBALDH1A1 | |
| SCHEMBL28875484 | 0.82 | POLB (0.49) | KDM4EMAPK1LMNAPOLBALDH1A1 | |
| SCHEMBL9986433 | 0.82 | NR4A2 (0.56) | KDM4ELMNAALDH1A1NPY5RHPGD | |
| SCHEMBL27820209 | 0.82 | KDM4E (0.43) | KDM4EMAPK1LMNAPOLBALDH1A1 | |
| SCHEMBL29573245 | 0.81 | ALDH1A1 (0.48) | KDM4EMAPK1LMNAPOLBALDH1A1 | |
| SCHEMBL8516062 | 0.78 | ALDH1A1 (0.46) | KDM4ELMNAPOLBALDH1A1HPGD | |
| SCHEMBL11844371 | 0.78 | NPY5R (0.45) | KDM4EMAPK1LMNAPOLBALDH1A1 | |
| SCHEMBL27890319 | 0.78 | KDM4E (0.45) | KDM4ELMNAALDH1A1NPY5RHPGD | |
| SCHEMBL29220048 | 0.78 | CNR1 (0.47) | KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102763-A2 | FSH MIMETICS FOR THE TREATMENT OF INFERTILITY | Applied Research Systems ARS Holding N.V. (AN) | 2001-05-30 | — | — | EP | claimed |
| WO-2000008015-A2 | FSH MIMETICS FOR THE TREATMENT OF INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2000-02-17 | — | — | WO | claimed |
| EP-1102763-A2 | FSH MIMETICS FOR THE TREATMENT OF INFERTILITY | Applied Research Systems ARS Holding N.V. (AN) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000008015-A2 | FSH MIMETICS FOR THE TREATMENT OF INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2000-02-17 | — | — | WO | disclosed |