SCHEMBL7838580

SCHEMBL7838580

C=CS(=O)(=O)CC[N]c1cccc(S(=O)(=O)O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP3 Q9H4L4 2/20 0.42
SENP2 Q9HC62 2/20 0.42
SENP1 Q9P0U3 2/20 0.42
SUMO2 P61956 1/20 0.42
SUMO1 P63165 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
TDP1 Q9NUW8 3/20 0.40
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
POLB P06746 1/20 0.36
CYP2D6 P10635 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
NOS1 P29475 1/20 0.35
CA2 P00918 6/20 0.34
CA9 Q16790 6/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759866 0.92 TDP1 (0.38) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL7843599 0.81 TDP1 (0.46) SENP2SUMO2SUMO1SENP7TDP1
SCHEMBL9627414 0.80 TDP1 (0.46) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL7843604 0.79 POLB (0.35) TSHRALDH1A1POLBCYP2D6SMN1; SMN2
SCHEMBL7803303 0.78 SENP3 (0.41) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL6240592 0.78 TSHR (0.47) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL7839508 0.73 TDP1 (0.37) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL7839760 0.73 TDP1 (0.43) TDP1TSHRALDH1A1KMT2APOLB
SCHEMBL3308193 0.71 SENP3 (0.62) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL3308195 0.71 SENP3 (0.62) SENP3SENP2SENP1SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed
US-5539088-A PROVIDE DYEINGS IN BRILLIANT SHADES WITH GOOD FASTNESS PROPERTIES AND HIGH DEGREE OF FIXATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0675172-A2 Water-solable azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed