SENP3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1712890	0.58	7/20
SCHEMBL4161888	0.56	7/20
SCHEMBL2622737	0.54	7/20
SCHEMBL3958375	1.00	6/20
SCHEMBL4693271	0.68	6/20
SCHEMBL2589316	0.60	6/20
SCHEMBL2589319	0.60	6/20
SCHEMBL2589308	0.60	6/20
SCHEMBL2541489	0.57	6/20
SCHEMBL2541491	0.57	6/20
SCHEMBL110923	0.54	6/20
SCHEMBL110924	0.54	6/20
SCHEMBL1436156	0.54	6/20
SCHEMBL4254801	0.54	6/20
SCHEMBL4254803	0.54	6/20
SCHEMBL1436155	0.53	6/20
SCHEMBL4869190	0.53	6/20
SCHEMBL414245	0.52	6/20
SCHEMBL2602447	0.48	6/20
SCHEMBL2592201	1.00	5/20

Clinical trials — most relevant to SENP3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS)	PHASE2	COMPLETED
Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival	PHASE1	UNKNOWN
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN
Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Circulating Markers for Ischemic Heart Disease	nan	RECRUITING
Apoptosis Markers in Aggressive Periodontitis	nan	COMPLETED
Autophagy Bladder Cancer	nan	UNKNOWN
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing	nan	RECRUITING
Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma	nan	UNKNOWN
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study	nan	COMPLETED
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)	nan	COMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
Role of Serum ADAM 17 (A Disintegrin And Metalloprotease 17) and Caspase 3 in Patients With Chronic Kidney Disease	nan	NOT_YET_RECRUITING
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure	nan	RECRUITING
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
An Analysis of Urinary Proteases as Biomarkers for Hepatocellular Carcinoma-101423	nan	COMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Identification of Molecular Marker of Coagulase-negative Staphylococci for the Diagnosis of Prosthetic Joint Infections	nan	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS	nan	RECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Genetic Determinants of Sudden Cardiac Death	nan	COMPLETED
Predictive Value of Maternal Blood Protein Signatures in Preterm Birth	nan	COMPLETED
Long Term Prediction of MASH-related HCC Risk by Proteomics	nan	NOT_YET_RECRUITING
Expression and Clinical Significance of IGHD in Pancreatic Cancer	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SENP3 binder may also engage these)

Protein	Name	Similarity
Q9EP97	—	0.998	Q9EP97 →
Q8BWQ5	—	0.991	Q8BWQ5 →
Q5XIX0	—	0.990	Q5XIX0 →
Q9UPV7	—	0.989	Q9UPV7 →
Q60700	—	0.989	Q60700 →
Q80UW3	—	0.988	Q80UW3 →
Q5BIR3	—	0.988	Q5BIR3 →
Q8N5Z5	—	0.988	Q8N5Z5 →
Q3V1D5	—	0.988	Q3V1D5 →
Q90932	—	0.987	Q90932 →
O76081	—	0.987	O76081 →
Q63553	—	0.987	Q63553 →
P0C6A0	—	0.987	P0C6A0 →
Q6ZMS7	—	0.987	Q6ZMS7 →
Q76I79	—	0.987	Q76I79 →
Q3UJD6	—	0.987	Q3UJD6 →
Q9Z148	—	0.986	Q9Z148 →
Q63449	—	0.986	Q63449 →
Q9BTV7	—	0.986	Q9BTV7 →
P11299	—	0.986	P11299 →
Q8N4L4	—	0.986	Q8N4L4 →
Q9Z0E3	—	0.986	Q9Z0E3 →
Q8NCU1	—	0.986	Q8NCU1 →
Q9D1Z2	—	0.986	Q9D1Z2 →
SENP2	Sentrin-specific protease 2	0.986	landscape →
O43310	—	0.986	O43310 →
TET3	Methylcytosine dioxygenase TET3	0.986	landscape →
Q8BV79	—	0.986	Q8BV79 →
USP19	Ubiquitin carboxyl-terminal hydrolase 19	0.986	landscape →
Q66650	—	0.986	Q66650 →