Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MPC2 | O95563 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1220483 | 0.90 | PPARG (0.72) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL8196242 | 0.88 | PPARG (0.66) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL12521693 | 0.86 | PPARG (0.64) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL19828517 | 0.84 | PPARG (0.69) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL6358262 | 0.84 | PPARG (0.69) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL18541507 | 0.84 | PPARG (0.69) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL15871068 | 0.83 | PPARG (0.82) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL9311827 | 0.83 | PPARG (0.64) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL7839019 | 0.81 | PPARG (0.42) | PPARGCYP3A4RXRAFFAR1PPARA | |
| SCHEMBL5805283 | 0.80 | PPARG (0.80) | PPARGCYP3A4RXRAFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579733-B1 | THIAZOLIDINEDIONE DERIVATIVES, PRODUCTION AND USE THEREOF | UPJOHN CO (US) | 2001-06-20 | — | — | EP | disclosed |