Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGAV | P06756 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1220487 | 0.89 | PPARG (0.47) | PPARGCYP3A4RXRAHPGDKCNH2 | |
| SCHEMBL8196247 | 0.87 | PPARG (0.42) | PPARGCYP3A4RXRAHPGDKCNH2 | |
| SCHEMBL8791799 | 0.84 | HPGD (0.54) | PPARGCYP3A4RXRAHPGDFFAR1 | |
| SCHEMBL9311838 | 0.82 | FFAR1 (0.43) | PPARGCYP3A4RXRAFFAR1 | |
| SCHEMBL7839014 | 0.81 | PPARG (0.64) | PPARGCYP3A4RXRAHPGDFFAR1 | |
| SCHEMBL9803869 | 0.81 | FFAR1 (0.42) | PPARGCYP3A4RXRAHPGDFFAR1 | |
| SCHEMBL8791594 | 0.79 | PPARG (0.41) | PPARGCYP3A4RXRAHPGDKCNH2 | |
| SCHEMBL5805537 | 0.79 | PPARG (0.53) | PPARGCYP3A4RXRAHRH3 | |
| SCHEMBL9326656 | 0.79 | HRH3 (0.48) | PPARGHPGDFFAR1PPARAHRH3 | |
| SCHEMBL8792213 | 0.78 | PPARG (0.52) | PPARGCYP3A4RXRAHPGDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579733-B1 | THIAZOLIDINEDIONE DERIVATIVES, PRODUCTION AND USE THEREOF | UPJOHN CO (US) | 2001-06-20 | — | — | EP | disclosed |