Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076741 | 0.88 | EPHX2 (0.54) | EPHX2EPHX1HPGDTSHRALDH1A1 | |
| SCHEMBL6075943 | 0.82 | MTNR1A (0.42) | HPGDSIGMAR1KMT2AMEN1CYP3A4 | |
| SCHEMBL7840877 | 0.75 | EPHX2 (0.46) | EPHX2EPHX1HPGDTSHRALDH1A1 | |
| SCHEMBL5337584 | 0.73 | EPHX2 (0.54) | EPHX2EPHX1HPGDNPC1RAB9A | |
| SCHEMBL6076801 | 0.73 | EPHX2 (0.53) | EPHX2EPHX1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL5340392 | 0.73 | EPHX2 (0.53) | EPHX2EPHX1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL5351385 | 0.73 | EPHX2 (0.53) | EPHX2EPHX1HPGDRAB9AKMT2A | |
| SCHEMBL5348981 | 0.73 | EPHX2 (0.53) | EPHX2EPHX1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL6075637 | 0.73 | EPHX2 (0.53) | EPHX2EPHX1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL6076703 | 0.72 | EPHX2 (0.54) | EPHX2EPHX1HPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077927-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058495-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | disclosed |