Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.42 |
| ▸ | PGK2 | P07205 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011490 | 0.85 | MAPT (0.41) | MAPTNPSR1CDC7DBF4PTPN2 | |
| SCHEMBL13469125 | 0.84 | MAPT (0.47) | MAPTNPSR1CDC7DBF4ALDH1A1 | |
| SCHEMBL8007529 | 0.81 | MAPT (0.44) | MAPTNPSR1CDC7DBF4ALDH1A1 | |
| SCHEMBL8010666 | 0.80 | CYP4F2 (0.48) | MAPTNPSR1CDC7DBF4ALDH1A1 | |
| SCHEMBL12407058 | 0.80 | MAPT (0.43) | MAPTNPSR1CDC7DBF4ALDH1A1 | |
| SCHEMBL7907090 | 0.76 | PLA2G4A (0.45) | MAPTNPSR1CDC7DBF4ALDH1A1 | |
| SCHEMBL6826976 | 0.75 | DAO (0.57) | MAPTCDC7DBF4ALDH1A1HPGD | |
| SCHEMBL2491602 | 0.75 | PLA2G4A (0.46) | MAPTNPSR1KDM4E | |
| SCHEMBL6030268 | 0.74 | CA12 (0.52) | MAPTCDC7DBF4ALDH1A1HPGD | |
| SCHEMBL160967 | 0.74 | CA12 (0.43) | MAPTCDC7DBF4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934295-B1 | NOVEL BI-AROMATIC DIBENZOFURAN DERIVATIVES AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND IN COSMETICS | CT INTERNAT DE (FR) | 2001-03-07 | — | — | EP | disclosed |
| EP-0934295-A1 | NOVEL BI-AROMATIC DIBENZOFURAN DERIVATIVES AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017659-A1 | NOVEL BI-AROMATIC DIBENZOFURAN DERIVATIVES AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-04-30 | — | — | WO | disclosed |