Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563465 | 0.89 | AOC3 (0.42) | AOC3TAAR1ALDH1A1TSHRALOX15 | |
| Hydrochloric Acid SCHEMBL6561671 | 0.86 | AOC3 (0.41) | HTR2CAOC3TAAR1ALDH1A1TSHR | |
| SCHEMBL12015994 | 0.80 | TSHR (0.48) | HTR2CHTR2BAOC3TAAR1HTR2A | |
| SCHEMBL22928386 | 0.80 | TNKS (0.37) | OGG1AOC3CYP19A1ALDH1A1TP53 | |
| SCHEMBL6483148 | 0.80 | TNKS (0.37) | OGG1AOC3CYP19A1ALDH1A1TP53 | |
| SCHEMBL11486874 | 0.79 | OGG1 (0.36) | OGG1AOC3TAAR1HTR2AALDH1A1 | |
| SCHEMBL3703681 | 0.78 | TAAR1 (0.40) | AOC3TAAR1ALDH1A1ALOX15 | |
| SCHEMBL22395252 | 0.78 | KMT2A (0.58) | HTR2BHTR2ACYP19A1TSHRMAPK1 | |
| SCHEMBL3703684 | 0.78 | TAAR1 (0.40) | AOC3TAAR1ALDH1A1ALOX15 | |
| SCHEMBL12352042 | 0.78 | KMT2A (0.58) | HTR2BHTR2ACYP19A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801644-A4 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE POULENC RORER PHARMA (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0801644-A1 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5556990-A | SQUALENE SYNTHASE INHIBITORS, ANTICHOLESTEROL AGENTS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-09-17 | — | — | US | disclosed |
| WO-1996018615-A1 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-06-20 | — | — | WO | disclosed |