SCHEMBL7839869

SCHEMBL7839869

COCNC(=O)C(C)(C)c1ccc2[nH]c(-c3cc(C)cc(C)c3)c(CCNC(=O)O)c2c1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 11/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6982574 0.91 GNRHR (0.48) GNRHR
SCHEMBL7839867 0.84 GNRHR (0.55) GNRHR
SCHEMBL7492563 0.82 GNRHR (0.52) GNRHR
SCHEMBL6986887 0.81 GNRHR (0.51) GNRHR
SCHEMBL6983295 0.77 GNRHR (0.49) GNRHR
SCHEMBL6983351 0.76 GNRHR (0.51) GNRHR
SCHEMBL6982575 0.76 GNRHR (0.53) GNRHR
SCHEMBL14424655 0.75 GNRHR (0.69) GNRHR
SCHEMBL6984508 0.75 GNRHR (0.49) GNRHR
SCHEMBL8020455 0.74 GNRHR (0.67) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095038-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE Merck & Co., Inc. (US) 2001-05-02 EP disclosed
WO-2000004013-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO., INC. (US) 2000-01-27 WO disclosed