Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.60 |
| ▸ | MAOB | P27338 | 11/20 | 0.56 |
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SDHA | P31040 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840027 | 1.00 | CALML3 (0.60) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5327031 | 0.88 | MAOB (0.49) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5327022 | 0.88 | MAOB (0.49) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14898018 | 0.87 | CALML3 (0.61) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8111357 | 0.85 | CALML3 (0.64) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5832691 | 0.85 | CALML3 (0.64) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5832684 | 0.85 | CALML3 (0.64) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL28109794 | 0.84 | CALML3 (0.65) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL7841802 | 0.84 | MAOA (0.74) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL7841797 | 0.84 | MAOA (0.74) | CALML3MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807112-B1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5910504-A | BACTERICIDES TREATING INFECTIONS | PHARMACIA & UPJOHN (US) | 1999-06-08 | — | — | US | disclosed |
| WO-1996023788-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |