Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629493 | 0.81 | TSHR (0.48) | ALDH1A1FUCA1MAPTL3MBTL1GAA | |
| SCHEMBL3179093 | 0.80 | MAPT (0.61) | ALDH1A1POLBFUCA1MAPTRECQL | |
| SCHEMBL3055063 | 0.79 | MAPT (0.42) | ALDH1A1POLBMAPTL3MBTL1RECQL | |
| SCHEMBL8630653 | 0.78 | TTR (0.57) | ALDH1A1POLBMAPTL3MBTL1NPSR1 | |
| SCHEMBL8273120 | 0.77 | ALDH1A1 (0.49) | ALDH1A1POLBFUCA1MAPTL3MBTL1 | |
| SCHEMBL1598651 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBFUCA1MAPTL3MBTL1 | |
| SCHEMBL10316427 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBFUCA1MAPTL3MBTL1 | |
| SCHEMBL1936670 | 0.77 | ALDH1A1 (0.51) | ALDH1A1POLBFUCA1MAPTL3MBTL1 | |
| SCHEMBL12299854 | 0.76 | ALDH1A1 (0.44) | ALDH1A1POLBFUCA1MAPTL3MBTL1 | |
| SCHEMBL12494900 | 0.76 | ALDH1A1 (0.44) | ALDH1A1POLBFUCA1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155020-A2 | FURO[3,2-B]PYRIDINES AS 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050426-A2 | FURO[3, 2-B]PYRIDINES AS 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |