Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366112 | 0.84 | HSD17B3 (0.49) | PTGER2MAPTTP53PTGER1LMNA | |
| SCHEMBL1366120 | 0.80 | HDAC3 (0.53) | PTGER2MAPTTP53PTGER1LMNA | |
| SCHEMBL7837075 | 0.80 | TSHR (0.51) | MAPTTP53HSD17B3MEN1ALDH1A1 | |
| SCHEMBL6988456 | 0.79 | HSD17B3 (0.69) | MAPTHSD17B3MEN1ALDH1A1CYP1A2 | |
| SCHEMBL8788236 | 0.79 | HSD17B3 (0.53) | PTGER2MAPTHSD17B3MEN1ALDH1A1 | |
| SCHEMBL11545122 | 0.74 | MEN1 (0.53) | PTGER2MAPTPTGER1HSD17B3MEN1 | |
| SCHEMBL9185113 | 0.73 | MAPT (0.64) | PTGER2MAPTTP53PTGER1HSD17B3 | |
| SCHEMBL4637311 | 0.72 | TSHR (0.81) | MAPTTP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7344478 | 0.71 | P2RX4 (0.54) | MAPTHSD17B3MEN1ALDH1A1CYP1A2 | |
| SCHEMBL1367874 | 0.70 | NPC1 (0.47) | MAPTTP53LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820450-B1 | N-substituted azaheterocyclic carboxylic acids and alkylesters thereof | NOVO NORDISK AS (DK) | 2001-09-12 | — | — | EP | disclosed |
| EP-0820450-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996031497-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |