SCHEMBL7840796

SCHEMBL7840796

C=CS(=O)(=O)CCNc1ccccc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.56
HTT P42858 2/20 0.56
ALDH1A1 P00352 4/20 0.40
GAA P10253 1/20 0.40
ADRA2C P18825 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ADRA2B P18089 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759876 0.94 MAPT (0.53) MAPTHTTALDH1A1GAAADRA2C
SCHEMBL10795158 0.78 MAPT (0.62) MAPTHTTALDH1A1GAAADRA2C
SCHEMBL7839373 0.76 ALDH1A1 (0.52) MAPTALDH1A1KEAP1MEN1KMT2A
SCHEMBL16281838 0.75 MAPT (0.58) MAPTHTTALDH1A1GAAADRA2C
SCHEMBL9852005 0.75 MAPT (0.58) MAPTHTTALDH1A1GAAADRA2C
SCHEMBL9816682 0.74 MAPT (0.56) MAPTHTTALDH1A1GAAADRA2C
SCHEMBL7828773 0.74 MAPT (0.56) MAPTHTTALDH1A1GAAADRA2C
SCHEMBL29379717 0.74 MAPT (1.00) MAPTHTTALDH1A1GAAADRA2C
SCHEMBL76608 0.74 MAPT (1.00) MAPTHTTALDH1A1GAAADRA2C
Hydrochloric Acid SCHEMBL2342540 0.72 MAPT (0.95) MAPTHTTALDH1A1GAAADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed
US-5539088-A PROVIDE DYEINGS IN BRILLIANT SHADES WITH GOOD FASTNESS PROPERTIES AND HIGH DEGREE OF FIXATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0675172-A2 Water-solable azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed