Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7831467 | 0.99 | SSTR4 (0.49) | SSTR4SSTR1GABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL7832311 | 0.83 | SSTR4 (0.50) | SSTR4SSTR1GABRDGABRA1GABRB1 | |
| SCHEMBL8347656 | 0.82 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8350781 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL4314996 | 0.80 | CA1 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13540024 | 0.78 | MAOA (0.46) | SSTR4GABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL4825172 | 0.78 | SSTR4 (0.44) | SSTR4SSTR1GABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL20137865 | 0.77 | SSTR4 (0.43) | SSTR4SSTR1GABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL29971297 | 0.77 | SSTR4 (0.43) | SSTR4SSTR1GABRDGABRA1GABRB1 | |
| SCHEMBL7839369 | 0.76 | SSTR4 (0.49) | SSTR4SSTR1GABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944388-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0944388-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1997038665-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | disclosed |