Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573958 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL3457059 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL17817475 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL5862608 | 0.88 | ALDH1A1 (0.65) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL11571023 | 0.81 | ALDH1A1 (0.69) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL24843168 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL13042709 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL24843157 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL12977043 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TAAR1NPSR1POLBTDP1 | |
| SCHEMBL24843163 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TAAR1NPSR1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |