⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896581 | 1.00 | — | — | |
| SCHEMBL27498307 | 0.89 | CA14 (0.39) | — | |
| SCHEMBL275280 | 0.82 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL10805452 | 0.79 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL26658220 | 0.79 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL1920162 | 0.77 | SMN1; SMN2 (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL8809999 | 0.77 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL177800 | 0.75 | — | — | |
| SCHEMBL225761 | 0.74 | — | — | |
| SCHEMBL18867261 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115297861-A | Compound and use thereof | 福宏治疗公司 | 2022-11-04 | — | — | CN | disclosed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |