Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8809999

COC(=O)C(C)C(=C(C(C)C(=O)OC)C(C)C(=O)OC)C(C)C(=O)OC.N.N

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
CA14 Q9ULX7 2/20 0.44
CA12 O43570 1/20 0.41
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
TAS1R3 Q7RTX0 2/20 0.32
TAS1R1 Q7RTX1 2/20 0.32
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
MME P08473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL275280 0.87 SMN1; SMN2 (0.52) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL10805452 0.84 SMN1; SMN2 (0.50) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL26658220 0.84 SMN1; SMN2 (0.50) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL1920162 0.81 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL9505582 0.79 SMN1; SMN2 (0.46) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL18867261 0.79
SCHEMBL858078 0.79
SCHEMBL4440882 0.79
SCHEMBL225761 0.79
Ammonia Solution, Strong SCHEMBL4405501 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997003137-A2 A JET INK PRINTING INK COMPOSITION THE GENERAL ELECTRIC COMPANY PLC (GB) 1997-01-30 WO disclosed