Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851879 | 0.90 | — | — | |
| SCHEMBL7851977 | 0.89 | ALDH1A1 (0.33) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7841731 | 0.89 | MEN1 (0.40) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL7849362 | 0.89 | MEN1 (0.40) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL7851421 | 0.87 | ALDH1A1 (0.32) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9694117 | 0.84 | MEN1 (0.36) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL7848981 | 0.81 | TOP2A (0.33) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL9694860 | 0.80 | MEN1 (0.48) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL9692946 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL7849214 | 0.79 | POLB (0.33) | ALDH1A1KDM4EHPGDPOLBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726270-B1 | Derivatives of 1,6-naphthyridone carboxylic acids | BAYER AG (DE) | 2001-05-23 | — | — | EP | claimed |
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | claimed |
| EP-0726270-B1 | Derivatives of 1,6-naphthyridone carboxylic acids | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | disclosed |