Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844285 | 0.92 | LTA4H (0.44) | SLC6A4PPARGPPARALTA4HADRA2A | |
| SCHEMBL11065085 | 0.91 | PPARG (0.44) | SLC6A4PPARGPPARALTA4HKDM4E | |
| SCHEMBL5050475 | 0.90 | LTA4H (0.44) | SLC6A4PPARGPPARALTA4HLMNA | |
| SCHEMBL28280512 | 0.89 | LTA4H (0.43) | SLC6A4LTA4HLMNAADRA2AADRA2B | |
| SCHEMBL28013972 | 0.89 | LTA4H (0.43) | SLC6A4LTA4HLMNAADRA2AADRA2B | |
| SCHEMBL28997989 | 0.89 | LTA4H (0.43) | SLC6A4LTA4HLMNAADRA2AADRA2B | |
| SCHEMBL23974956 | 0.88 | PPARG (0.41) | SLC6A4PPARGPPARALTA4HMTNR1A | |
| SCHEMBL8349925 | 0.88 | SLC6A4 (0.39) | SLC6A4PPARGPPARALTA4HKDM4E | |
| SCHEMBL1454315 | 0.87 | SLC6A4 (0.36) | SLC6A4PPARGPPARALTA4HKDM4E | |
| SCHEMBL22798634 | 0.87 | LTA4H (0.42) | SLC6A4LTA4HLMNAADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| CN-107632461-B | Varnish for photo-alignment film and liquid crystal display device | 株式会社日本显示器 | 2021-07-27 | — | — | CN | disclosed |
| CN-108690493-B | Varnish for photo-alignment film and liquid crystal display device | 株式会社日本显示器 | 2021-07-27 | — | — | CN | disclosed |
| US-4304683-A | Composition for liquid crystal color display element | MITSUI TOATSU CHEMICALS, INC. (JP) | 1981-12-08 | — | — | US | disclosed |