Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.59 |
| ▸ | KDM5C | P41229 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.59 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.59 |
| ▸ | KDM4A | O75164 | 4/20 | 0.59 |
| ▸ | KDM6B | O15054 | 3/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.59 |
| ▸ | KDM5A | P29375 | 2/20 | 0.59 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.59 |
| ▸ | TET3 | O43151 | 1/20 | 0.59 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ASPH | Q12797 | 1/20 | 0.59 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.59 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.59 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.59 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.59 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40123 | 0.98 | KDM4C (0.61) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| SCHEMBL31547893 | 0.96 | KDM4C (0.59) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| Hydrochloric Acid SCHEMBL7221156 | 0.96 | KDM4C (0.59) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| Methane SCHEMBL9122275 | 0.96 | KDM5C (0.59) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| Hydrogen Sulfide SCHEMBL27953098 | 0.90 | KDM5C (0.53) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| Isonicotinic Acid SCHEMBL28210508 | 0.90 | NAPRT (0.63) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| Alcohol SCHEMBL28687926 | 0.89 | KDM5B (0.52) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| Tert-Butanol SCHEMBL27878420 | 0.89 | KDM4C (0.52) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| SCHEMBL27623752 | 0.83 | RECQL (0.47) | KDM4CKDM5CKDM4EKDM2AKDM3A | |
| Bromide SCHEMBL3611932 | 0.82 | SMARCA2 (0.47) | KDM4CKDM5CKDM4EKDM2AKDM3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763530-B1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | BAYER AGROCHEM KK (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5849767-A | Chloropyridylcarbonyl derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0763530-A1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | NIHON BAYER AGROCHEM K.K. (JP) | 1997-03-19 | — | — | EP | disclosed |